THIOPENTONE-PROPOFOL HYPNOTIC SYNERGISM IN PATIENTS

Thiopentone-propofol hypnotic synergism in patients.

The hypnotic effects of thiopentone, propofol and their combination were studied in 120 unpremedicated ASA group I patients. The end-point for induction of anaesthesia was taken as inability to open the eyes to command 60 s after the end of injection. The dose-response curves were determined by probit analysis. Isobolographic and algebraic (fractional) analyses were used to assess quantitativel...

Thiopentone or propofol for LMA insertion?

We read the article by Bapat et al., 1 with interest. They demonstrated the good quality of laryngeal mask (LMA) insertion with midazolam-thiopentone and the poor conditions with lidocainethiopentone. We would like to bring to your attention two studies we published earlier this year. In the first 2 we showed that topical 40 mg lidocaine followed by 5 mg-kg -1 thiopentone produced conditions fo...

Changes in haemodynamic variables with thiopentone, methohexitone, propofol and etomidate.

Propofol anaesthesia in paediatric ambulatory patients: a comparison with thiopentone and halothane.

The purpose of this study was to evaluate the haemodynamic changes during induction, as well as the speed and quality of recovery when propofol (vs thiopentone and/or halothane) was used for induction and maintenance of anaesthesia in paediatric outpatients. One hundred unmedicated children, 3-12-yr-old, scheduled for ambulatory surgery were studied. The most common surgical procedures performe...

Midazolam Co-induction with Thiopentone and Propofol : a Comparative Study

Most commonly we use thiopentone and propofol as I.V.induction agent for General anaesthesia. They have many characteristics similar to ideal induction agent but also have dose related side effects. To decrease these side effects we may use the small dose of drug before induction which act synergistically with thiopentone and propofol in central nervous system to produce induction and the durg ...